December 7, 2022–Arts Etc.
Daily Use Of Lozenge Containing Arginine And Probiotics May Benefit Children With Dental Caries
Daily use of lozenge containing arginine and probiotics may benefit children with dental caries suggests a new study published in the Journal of Dentistry.
A study was done to investigate the effect of daily use of a lozenge containing arginine and probiotics for 10–12 months on caries increment, gingivitis- and plaque occurrence in children aged 5–9 years.
In this placebo-controlled, double-blinded, parallel-grouped randomized clinical trial, 343 children were randomly assigned to one of the study arms (1:1). The intervention group (n = 172) received a lozenge containing Lacticaseibacillus rhamnosus, LGG® (DSM33156), Lactobacillus paracasei subsp. Paracasei, L. CASEI 431® (DSM33451) and prebiotic (arginine 2%). The placebo group (n = 171) received an identical lozenge without arginine or probiotics. Primary canines and molars, and permanent first molars were examined clinically (d/D= ICDAS1–6) and radiographically (d/D = R1–6) at baseline and follow-up. Missing (m/M), sealed (s/S), and filled (f/F) surfaces (-s/-S) in both dentitions were also included. Utilizing clinical and radiographic scorings, caries experience was classified as dICDAS1–6msf-s (primary teeth), DICDAS1–6MSF-S (permanent teeth), d/DICDAS1–6 m/M-s/S-f/F-s/S (mixed dentition). A weighted and an unweighted score system was applied.
Results
The study was completed by 288 children. The dropout rate was 15%. The increase in ∆mean dICDAS3–6msf-s and ∆mean d/DICDAS3–6m/M-s/S-f/F-s/S was lower in the intervention group (p = 0.007). No differences were found for gingivitis- and plaque occurrence. No product-related side effects were reported. This study followed ICH-GCP including external monitoring.
Daily consumption of a lozenge containing prebiotic arginine and two strains of probiotics showed safe use and statistically significantly reduction in caries incrementbut no effect on the mean plaque or gingivitis occurrence in children. The use of a lozenge with arginine and probiotics combined has a promising potential as a supplementary tool for future management of caries.
The combination of prebiotic arginine and probiotics shows clinical potential as a supplementary approach to toothbrushing with fluoride toothpaste in managing caries increment in children. A new era in the management of caries may be emerging.
Keywords: Randomized clinical trial; Caries; Probiotics; Arginine; Synbiotic; Pediatric dentistry
Reference:
Camilla Juhl Pørksen, Mette Kirstine Keller, Anders Damholt, Amalie Kruse Sigersted Frederiksen, Kim Rud Ekstrand, Merete Markvart, Tove Larsen, Azam Bakhshandeh,
The effect of a lozenge combining prebiotic arginine and probiotics on caries increment in children during 10–12 months, a randomized clinical trial, Journal of Dentistry, Volume 135,
2023, 104599, ISSN 0300-5712. Https://doi.Org/10.1016/j.Jdent.2023.104599.
Keywords:
Daily, use, lozenge, containing, arginine, probiotics, may, benefit, children, with, dental, caries, Camilla Juhl Pørksen, Mette Kirstine Keller, Anders Damholt, Amalie Kruse Sigersted Frederiksen, Kim Rud Ekstrand, Merete Markvart, Tove Larsen, Azam Bakhshandeh, Journal of Dentistry
Journal Information
Aims and scope of journalJournal metricsAbstracted/indexed inISSN and eISSN
Aims and ScopeEvidence-Based Dentistry (EBD) aims to create a dialogue between dental practitioners and dental researchers, in order to drive new research and promote the use of the best available evidence to inform clinical decision making. We ensure that the journal has a clear focus on those areas that are most useful to practitioners, evaluating the evidence and providing guidance concerning the value of the author's conclusions.
EBD covers the full scope of dental and oral health disciplines, including dental and maxillofacial radiology, dental public health, endodontics, oral and maxillofacial pathology, oral medicine, oral microbiology, orthodontics, paediatric dentistry, periodontology, prosthodontics, restorative dentistry and special care dentistry.
Evidence-Based Dentistry is published by Springer Nature on behalf of the British Dental Association. Members receive the journal as part of their membership. The journal is bound into the British Dental Journal quarterly and is available through an institutional and personal subscription.
EBD publishes two article types: invited commentaries and peer-reviewed systematic reviews.Commentaries are by invitation only. We welcome submissions of systematic reviews via the EBD submission portal.
Receive Evidence-Based Dentistry's current issue table of contents.
Journal MetricsArticle metrics such as number of downloads, citations and online attention are available from each article page, and provide an overview of the attention received by a paper.
2022 Citation MetricsSNIP**: 0.375SJR***: 0.255
**Source-normalized Impact per Paper (Scopus)***SCImago Journal Rank (Scopus)
2022 Peer Review MetricsSubmission to first editorial decision: 13 daysSubmission to Accept: 92 days
2022 Usage MetricsDownloads: 385,890Altmetric mentions: 655
Abstracted/indexed in:The international standard serial number (ISSN) for Evidence-Based Dentistry is 1462-0049, and the electronic international standard serial number (eISSN) is 1476-5446
Fluent™ Data Used By The School Of Dentistry At Indiana University In Pediatric Dentistry Trends In The Use Of Amalgam And Resin Composite Study
The study is the twelfth published article produced in partnership with IU's School of Dentistry and appears in the Journal of the American Dental Association (JADA)
HAMILTON, N.J., Aug. 22, 2023 /PRNewswire/ -- Fluent, the premier dental insights company delivering customized, actionable business intelligence to support a variety of dental stakeholder objectives, announced that its research partnership with the School of Dentistry at Indiana University has produced another article selected for peer-reviewed publication and was co-authored by Fluent's Chief Analytics Officer, Tim Downey.
The study, published in the August 2023 Journal of the American Dental Association (JADA), is titled "Amalgam or composite in pediatric dentistry: Analysis of private insurance claims data." JADA is the nation's premier dental journal. This article is the 13th published study using Fluent data and the 12th in collaboration with Indiana University.
The study examined the trends in the use of amalgam and resin composite in the United States using data gleaned from insurance claims submitted from January 2010 through March 2020. The study revealed that girls were less likely to receive amalgam than boys and that the use of amalgam is trending down, with the sharpest decline noted in 2014. The article is currently available on the JADA website (subscription only). An abstract can be found at: https://jada.Ada.Org/article/S0002-8177(23)00262-3/fulltext
Paul T. Sheils, CEO of Fluent, stated: "We are excited that our ongoing partnership with the School of Dentistry at Indiana University continues to reveal such interesting, relevant information, and we are proud to share the results of this study with the readers of JADA, a publication held in the highest regard by dentists and dental industry leaders."
For more information about Fluent and our dental business intelligence solutions, visit https://Fluent.Dental.
For business inquiries, please contact Fluent Business Development at (856) 986-6216 or email insights@fluent.Dental
About Fluent™ Fluent, formerly known as P&R Dental Strategies, is the only dental source that combines comprehensive historical and current dental procedure data with technology, analytics, research and dental domain expertise to address the questions and business concerns of our customers and partners. Fluent's 25+ years of trusted expertise gives us unique insight into how the oral healthcare ecosystem operates. We harness that experience and combine it with the power of our multi-payer dental claims database of commercially insured members, primary research and data management best practices to enable all stakeholders in the oral health industry to thrive.
Website: Fluent.Dental LinkedIn: linkedin.Com/company/fluentdental Twitter: twitter.Com/FluentDental
Joe Mann Vice President, Marketing Fluent (609) 783-9011insights@fluent.Dental
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